PC-FACS
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August 19 - Special Issue: Bioethics
Bias in reporting of end points of efficacy and toxicity in randomized, clinical trials for women with breast cancer. |
Vera-Badillo FE, Shapiro R, Ocana A, Amir E, Tannock IF. |
Bias in Reporting of End Points and Toxicity in Breast Cancer Clinical Trials Background: Biased reporting of clinical trials creates false perceptions of drug efficacy and safety; "spin" (ie, statem... |
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Toward patient-centered cancer care: Patient perceptions of problematic events, impact, and response. |
Mazor KM, Roblin DW, Greene SM, et al. |
Cancer Patients' Perceptions of Preventable, Harmful Events Background: Communication is integral to patient-centered care; when care goes wrong, communication with patients and families often falter... |
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Therapeutic misconception, misestimation, and optimism in participants enrolled in phase 1 trials. |
Pentz RD, White M, Harvey RD, et al. |
Phase 1 Trial Participants' Misconceptions, Misestimation, and Optimism Background: Most patients misunderstand the purpose of a phase 1 trial1,2 and enroll for therapeutic benefits, despite the low... |
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Time to stop worrying about the therapeutic misconception. |
Wendler DS. |
Time to Stop Worrying About Therapeutic Misconception Background: Patients enrolled or considering enrollment in clinical trials often fail to understand the differences between clinical trials and c... |
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The potential benefit of the placebo effect in sham-controlled trials: Implications for risk-benefit assessments and informed consent [published online ahead of print December 13, 2012]. |
Brim RL, Miller FG. |
Potential Benefit of Placebo in Sham-Controlled Trials Background: In trials of medical and surgical procedures, sham placebos are often considered "nontherapeutic" interventions that place particip... |
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Predictors of newly diagnosed cancer patients' understanding of the goals of their care at initiation of chemotherapy. |
Lennes IT, Temel JS, Hoedt C, Meilleur A, Lamont EB. |
Predictors of Patients' Understanding of Goals of Cancer Care Background: One-third of patients who undergo treatment for incurable cancer overestimate their prognosis compared with their physicians... |
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